Here is the television schedule for the opening weekend of the 1999 MLS season:
| Date | Matchup | Kickoff (ET) | Television |
| March 20 | D.C. United at Tampa Bay | 7:00 p.m. | Newschannel 8 (Washington, D.C.) |
| March 20 | MetroStars at Miami | 8:00 p.m. | espn2 |
| March 20 | Kansas City at Dallas | 8:30 p.m. | MetroSports (KC) |
| March 20 | Colorado at Los Angeles | 10:30 p.m. | Fox Sports Rocky Mtn. |
| March 20 | Chicago at San Jose | 11:00 p.m. | Fox Sports Chicago/Fox Sports Bay Area |