The following is the 1998 Tampa Bay Mutiny schedule. Please note that all times listed are eastern and everything is subject to change.
| Date | Opponent | Kickoff |
| March 21 | Columbus | 7:30 p.m. |
| March 26 | Miami | 7:30 p.m. |
| April 4 | at Chicago | 8:00 p.m. |
| April 11 | Dallas | 7:30 p.m. |
| April 19 | at Colorado | 3:00 p.m. |
| April 25 | at Los Angeles | 10:30 p.m. |
| April 30 | Columbus | 7:30 p.m. |
| May 3 | MetroStars | 3:00 p.m. |
| May 10 | at New England | 3:00 p.m. |
| May 13 | Kansas City | 7:30 p.m. |
| May 16 | Chicago | 7:30 p.m. |
| May 23 | at D.C. United | 7:30 p.m. |
| May 30 | D.C. United | 7:30 p.m. |
| June 3 | at MetroStars | 7:30 p.m. |
| June 6 | at Kansas City | 8:30 p.m. |
| June 21 | at Dallas | 7:00 p.m. |
| June 27 | at Miami | 7:30 p.m. |
| July 4 | New England | 7:30 p.m. |
| July 11 | at MetroStars | 7:00 p.m. |
| July 15 | Los Angeles | 7:30 p.m. |
| July 18 | at San Jose | 10:30 p.m. |
| July 25 | Colorado | 7:30 p.m. |
| July 29 | at D.C. United | 7:30 p.m. |
| Aug. 6 | Miami | 7:30 p.m. |
| Aug. 14 | New England | 7:30 p.m. |
| Aug. 22 | at Columbus | 7:30 p.m. |
| Aug. 29 | D.C. United | 7:30 p.m. |
| Sept. 3 | San Jose | 8:00 p.m. |
| Sept. 13 | MetroStars | 5:30 p.m. |
| Sept. 19 | at New England | 7:30 p.m. |
| Sept. 24 | at Columbus | 8:00 p.m. |
| Sept. 27 | at Miami | 3:00 p.m. |