Here is the 1999 Colorado Rapids schedule. Please note that all times are MT and that the schedule is subject to change.
| Date | Opponent | Time (MT) |
| Sat. March 20 | at Los Angeles | 8:30 p.m. |
| Sat. March 27 | at San Jose | 8:00 p.m. |
| Sat. April 10 | Miami | 7:00 p.m. |
| Sat. April 17 | Kansas City | 7:00 p.m. |
| Sat. May 1 | at New England | 5:30 p.m. |
| Sat. May 8 | at Dallas | 6:30 p.m. |
| Sun. May 16 | at Chicago | 3:00 p.m. |
| Sat. May 22 | MetroStars | 7:00 p.m. |
| Thu. May 27 | San Jose | 7:30 p.m. |
| Thu. June 3 | at San Jose | 8:30 p.m. |
| Sat. June 12 | at MetroStars | 5:00 p.m. |
| Sat. June 19 | Dallas | 7:00 p.m. |
| Sat. June 26 | Chicago | 7:00 p.m. |
| Sun. July 4 | Columbus | 7:00 p.m. |
| Wed. July 7 | at Kansas City | 6:00 p.m. |
| Sat. July 10 | at D.C. United | 5:30 p.m. |
| Sun. July 25 | Tampa Bay | 7:00 p.m. |
| Wed. July 28 | Los Angeles | 7:00 p.m. |
| Sat. July 31 | at Dallas | 6:30 p.m. |
| Fri. Aug. 6 | New England | 7:00 p.m. |
| Sun. Aug. 8 | at Chicago | 11:00 a.m. |
| Fri. Aug. 13 | at Tampa Bay | 5:30 p.m. |
| Wed. Aug. 18 | Dallas | 7:00 p.m. |
| Sat. Aug. 28 | D.C. United | 7:00 p.m. |
| Sat. Sept. 4 | at Columbus | 5:30 p.m. |
| Fri. Sept. 10 | Kansas City | 7:00 p.m. |
| Sat. Sept. 18 | Los Angeles | 7:00 p.m. |
| Sat. Sept. 25 | at Kansas City | 6:30 p.m. |
| Wed. Sept. 29 | at Los Angeles | 8:30 p.m. |
| Fri. Oct. 1 | San Jose | 7:00 p.m. |
| Wed. Oct. 6 | Chicago | 7:00 p.m. |
| Sat. Oct. 9 | at Miami | 5:30 p.m. |