| DATE | NETWORK | MATCH | TIME |
| April 6 | ESPN | Washington at San Jose | 8:00 p.m. |
| April 14 | Univision | San Jose at Dallas | 3:00 p.m. |
| April 18 | ESPN2 | Kansas City at Dallas | 8:30 p.m. |
| April 21 | Univision | Kansas City at San Jose | 4:00 p.m. |
| April 28 | Univision | Dallas at Tampa Bay | 3:00 p.m. |
| May 2 | ESPN2 | Columbus at Kansas City | 8:30 p.m. |
| May 5 | Univision | Washington at Los Angeles | 4:00 p.m. |
| May 11 | ESPN2 | Tampa Bay at Colorado | 4:30 p.m. |
| May 12 | Univision | NY/NJ at Washington | 3:00 p.m. |
| May 16 | ESPN2 | Colorado at NY/NJ | 7:30 p.m. |
| May 19 | Univision | NY/NJ at New England | 3:00 p.m. |
| May 23 | ESPN2 | Tampa Bay at Dallas | 7:30 p.m. |
| May 26 | Univision | Columbus at Los Angeles | 4:00 p.m. |
| May 30 | ESPN2 | Washington at NY/NJ | 7:30 p.m. |
| June 2 | Univision | NY/NJ at Dallas | 3:00 p.m. |
| June 6 | ESPN2 | Los Angeles at New England | 7:30 p.m. |
| June 8 | ESPN | Kansas City at Columbus | 1:30 p.m. |
| June 9 | Univision | Los Angeles at NY/NJ | 3:00 p.m. |
| June 16 | Univision | San Jose at NY/NJ | 3:00 p.m. |
| June 20 | ESPN2 | Washington at Kansas City | 9:00 p.m. |
| June 23 | Univision | San Jose at NY/NJ | 3:00 p.m. |
| June 27 | ESPN2 | Columbus at New England | 7:00 p.m. |
| June 30 | Univision | NY/NJ at Columbus | 3:00 p.m. |
| July 4 | ESPN2 | Columbus at Tampa Bay | 7:30 p.m. |
| July 7 | Univision | Los Angeles at Kansas City | 3:00 p.m. |
| July 11 | ESPN2 | New England at Columbus | 7:30 p.m. |
| July 14 | Univision | MLS All-Star Game (at NY/NJ) | TBA |
| July 18 | ESPN2 | Kansas City at Tampa Bay | 7:30 p.m. |
| July 20 | ESPN | Washington at New England | 12 noon |
| July 21 | Univision | Tampa Bay at Colorado | 3:00 p.m. |
| July 25 | ESPN2 | Tampa Bay at Columbus | 7:30 p.m. |
| July 28 | Univision | San Jose at NY/NJ | 3:00 p.m. |
| Aug. 1 | ESPN2 | Los Angeles at Colorado | 7:30 p.m. |
| Aug. 3 | ESPN | NY/NJ at New England | 1:00 p.m. |
| Aug. 4 | Univision | Kansas City at Washington | 3:00 p.m. |
| Aug. 8 | ESPN2 | New England at Los Angeles | 9:00 p.m. |
| Aug. 11 | Univision | Los Angeles at Kansas City | 3:00 p.m. |
| Aug. 15 | ESPN | San Jose at Kansas City | 9: 00 p.m. |
| Aug. 16 | ESPN | Los Angeles at Washington | 8:30 p.m. |
| Aug. 18 | Univision | San Jose at Columbus | 3:00 p.m. |
| Aug. 22 | ESPN2 | Dallas at San Jose | 10:00 p.m. |
| Aug. 25 | Univision | Tampa Bay at Washington | 3:00 p.m. |
| Aug. 29 | ESPN2 | Washington at Colorado | 8:30 p.m. |
| Sept. 1 | Univision | Dallas at Washington | 3:00 p.m. |
| Sept. 5 | ESPN2 | Colorado at Los Angeles | 10:30 p.m. |
| Sept. 8 | Univision | San Jose at Colorado | 3:00 p.m. |
| Sept. 10 | ESPN | Los Angeles at NY/NJ | 7:30 p.m. |
| Sept. 12 | ESPN2 | Washington at Tampa Bay | 7:00 p.m. |
| Sept. 14 | ESPN | Tampa Bay at New England | 5:00 p.m. |
| Sept. 15 | Univision | NY/NJ at Columbus | 3:00 p.m. |
| Sept. 17 | ESPN | New England at Washington | 7:30 p.m. |
| Sept. 19 | ESPN2 | Los Angeles at Dallas | 7:30 p.m. |
| Sept. 22 | Univision | Dallas at Los Angeles | 4:00 p.m. |
| Sept. 24 | ESPN | Quarterfinal | 7:30 p.m. |
| Sept. 29 | ESPN2 | Quarterfinal | 8:30 p.m. |
| Oct. 3 | ESPN2 | *Quarterfinal | 7:30 p.m. |
| Oct. 5 | ESPN2 | Semifinal | 7:30 p.m. |
| Oct. 12 | ESPN2 | Semifinal | 5:00 p.m. |
| Oct. 16 | ESPN | *Semifinal | 9:00 p.m. |
| Oct. 20 | ABC | Final | 3:30 p.m. |
| *match played if necessary in best-of-three series. |
