Here is the MLS schedule for the upcoming weekend
| Date | Matchup | Kickoff (ET) | Television |
| March 21 | Chicago at Miami | 7:30 p.m. | Sunshine Network; Fox Sports Chicago Plus |
| March 21 | Columbus at Tampa Bay | 8:00 p.m. | WSYX-Columbus |
| March 21 | Kansas City at D.C. United | 8:00 p.m. | ESPN2 |
| March 21 | Colorado at Dallas | 8:30 p.m. | Fox Sports Rocky Mtn. |
| March 21 | San Jose at Los Angeles | 10:00 p.m. | KICU-San Jose |